Pharma & Lab Sonication Applications

Sonication uses high-frequency ultrasonic energy to improve mixing, dispersion and processing. LeelaSonic offers sonicator baths, probe sonicators, and baths with chillers to support stable results in pharma, biotech, R&D and QC laboratories.

R&D / QC friendly Dispersion & degassing Chiller for heat-sensitive samples Probe for high intensity
Common Sonication Use-Cases

Choose the right solution based on sample volume, viscosity, intensity needed and temperature sensitivity.

Dispersion & Deagglomeration

Breaks particle agglomerates and improves dispersion uniformity in suspensions.
Nanoparticles Pigments API dispersion

Emulsification

Produces finer emulsions and stable mixtures for formulations and R&D trials.
O/W & W/O Formulation Mix stability

Degassing

Removes dissolved gases from solvents and solutions to reduce bubbles and improve process stability.
Solvents Resins Sample prep

Cell Lysis / Homogenization

Probe sonication for efficient cell disruption and homogenization (protocol dependent).
Biotech Protein extraction High intensity

Heat-Sensitive Samples

Bath-with-chiller keeps temperature controlled during longer sonication cycles.
Chiller Temperature control Long cycles

Lab Glassware / Instrument Cleaning

Sonicator bath supports routine cleaning for lab glassware and instruments (chemistry dependent).
Glassware Burettes Pipettes
Recommended Products: Sonicator Bath / Probe Sonicator / Bath with Chiller
We can suggest the best model based on volume, intensity and temperature requirements.
Tip: For repeatable results, always define sample volume, container type, sonication time (pulse/continuous) and temperature limit. If you share your protocol goal, we can recommend a suitable configuration.
How to Choose the Right Sonication System

Sample Volume

Small vials to beakers—bath is ideal for gentle processing; probe is preferred for high intensity at low-to-medium volumes.

Intensity Needed

If you need strong cell disruption or fast dispersion, probe sonicator is usually the right choice.

Temperature Sensitivity

Heat builds during sonication. If samples are heat-sensitive, select a bath with chiller or cooling approach.

Chemistry Compatibility

Solvent and container compatibility matter. Tell us solvent type and desired safety features.

Cycle Time / Throughput

For multiple samples per batch, bath systems are convenient. For one-at-a-time high energy, probe is faster.

Repeatability & SOP

Define time, amplitude, pulse settings and temperature window for consistent results in QC / R&D.
Send us: sample volume, application goal, solvent type, temperature limit, and expected throughput.
We will recommend the right sonicator model and configuration.
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